Diagnóstico tardio de Doença de Crohn Fibroestenosante-Fistulizante: relato de caso
نویسندگان
چکیده
Objetivo: Relatar o caso de um paciente com atraso diagnóstico 15 anos para Doença Crohn (DC) Fibroestenosante-Fistulizante, diagnosticada em fase avançada fístula entero-sigmoidea, descrevendo curso clínico e as intervenções realizadas. Detalhamento do caso: Paciente masculino, 27 anos, tabagista, relato dor abdominal crônica associada a quadros diarreicos desde os 14 anos. Exames laboratoriais evidenciando elevação provas inflamatórias anticorpo anti-Saccharomyces cerevisiae (ASCA) positivo. Colonoscopia alterações sugestivas DC ativa enteroressonância regiões estenose íleo distal íleo-sigmoidea indicação abordagem cirúrgica. O apresentou refratária à corticoterapia, demandando múltiplas otimizações terapêuticas troca imunobiológico Infliximabe (IFX) Adalimumabe (ADA) devido ao desenvolvimento resistência imune IFX, resolução cicatricial às custas ampliação das áreas estenose, mantendo padrões exacerbação remissão da doença. Considerações finais: aos sintomas inespecíficos, intermitente perda seguimento paciente, além tabagismo, foram fundamentais progressão processo inflamatório crônico perfil mais agressivo
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ژورنال
عنوان ژورنال: Revista Eletrônica Acervo Saúde
سال: 2023
ISSN: ['2178-2091']
DOI: https://doi.org/10.25248/reas.e12519.2023